| Date | Location | Result | |
| 03/11/10 | Cleveland, Ohio (Quicken Loans Arena) | Miami 73, Buffalo 59 | Box score |
| 03/07/10 | Alumni Arena (Buffalo, NY) | Buffalo 72, Toledo 54 | Box score |
| 03/04/10 | Millett Hall, Oxford, Ohio | Miami 73, Buffalo 62 | Box score |
| 02/27/10 | Alumni Arena (Buffalo, NY) | Buffalo 72, Ohio 69 | Box score |
| 02/24/10 | Rhodes Arena - Akron, Ohio | Akron 77, Buffalo 67 | Box score |
| 02/20/10 | Jersey City, NJ (Yanitelli Center) | Buffalo 77, Saint Peter's College 75 | Box score |
| 02/17/10 | Alumni Arena (Buffalo, NY) | Buffalo 64, Bowling Green 51 | Box score |
| 02/13/10 | Alumni Arena (Buffalo, NY) | Buffalo 70, Kent State 55 | Box score |
| 02/10/10 | Alumni Arena (Buffalo, NY) | Buffalo 84, Eastern Michigan 67 | Box score |
| 02/06/10 | Savage Arena (Toledo, OH) | Buffalo 65, Toledo 59 | Box score |
| 02/04/10 | Mount Pleasant, Mich. (Rose Center) | Central Michigan 88, Buffalo 82 | Box score |
| 02/01/10 | Alumni Arena (Buffalo, NY) | Western Michigan 85, Buffalo 70 | Box score |
| 01/30/10 | Convocation Center (DeKalb, Ill.) | Buffalo 95, Northern Illinois 83 | Box score |
| 01/28/10 | Alumni Arena (Buffalo, NY) | Ball State 75, Buffalo 69 | Box score |
| 01/23/10 | Athens, Ohio (Convocation Center) | Ohio 99, Buffalo 77 | Box score |
| 01/20/10 | Kent, Ohio - M.A.C. Center | Kent State 89, Buffalo 54 | Box score |
| 01/17/10 | Alumni Arena (Buffalo, NY) | Buffalo 78, Akron 65 | Box score |
| 01/14/10 | Bowling Green, Ohio | Buffalo 68, Bowling Green 65 | Box score |
| 01/09/10 | Alumni Arena (Buffalo, NY) | Buffalo 73, Miami 55 | Box score |
| 12/30/09 | Orlando, Fla. (UCF Arena) | Buffalo 81, Liberty 64 | Box score |
| 12/29/09 | Orlando, Fla. (UCF Arena) | Jacksonville 83, Buffalo 73 | Box score |
| 12/22/09 | Resch Center (Green Bay, Wis.) | Buffalo 71, Green Bay 65 | Box score |
| 12/12/09 | Alumni Arena (Buffalo, NY) | Buffalo 93, Buffalo State 65 | Box score |
| 12/09/09 | 'Taps' Gallagher Center | Buffalo 86, Niagara 80 | Box score |
| 12/05/09 | Mackey Arena - West Lafayette, IN | Purdue 101, Buffalo 65 | Box score |
| 12/03/09 | Alumni Arena (Buffalo, NY) | Buffalo 74, Army 67 | Box score |
| 11/24/09 | Alumni Arena (Buffalo, NY) | Canisius 73, Buffalo 71 | Box score |
| 11/21/09 | Towson Center, Towson, Md. | Buffalo 78, Towson 69 | Box score |
| 11/19/09 | Annapolis, Md. - Alumni Hall | Buffalo 63, Navy 53 | Box score |
| 11/15/09 | Alumni Arena (Buffalo, NY) | Vermont 58, Buffalo 57 | Box score |